[대학원 생명과학과 세미나 안내]
연사 : 서진수 교수 (DGIST 뇌인지과학전공)
연제 : Investigating cell type-specific role of ApoE4 in Alzheimer’s disease using human induced pluripotent stem cells
일시 : 2019년 11월 15일 (금) 오후 5시
장소 : 하나과학관 A동 B131호
초청교수 : 이은진 교수
Abstract
Tremendous efforts have been made to cure Alzheimer’s disease (AD) over 100 years since the disease was first identified, however, we still don’t have a clear understanding of what causes the onset of disease and what are the underlying mechanisms. In this talk, I will present my recent works utilizing human induced pluripotent stem cells (hIPSCs) and the genome editing tool to investigate cell-type-specific pathological effects of APOE4; the strongest genetic risk factor for AD, and discuss how this genetic platform can be employed for unraveling mechanistic insights into AD pathogenesis as well as identifying potential therapeutics to combat AD.