[대학원 생명과학과 세미나 안내]
연사 : 이창한 교수(아주대학교)
연제 : Bacterial protein homeostasis for host invasion
일시 : 2021년 09월 10일 (금) 오후 5시
장소 : 온라인 화상 강의로 진행됩니다.
초청교수 : 이은진 교수
Abstract
Microorganisms are directly exposed to various stresses in their environment that threaten their survival. In order to cope with these damaging conditions, bacteria need to immediately sense changes in the environment and react rapidly and accordingly. Some types of stressors, such as temperature change, desiccation, and acidity, negatively impact protein stability. Since proteins are essential for various molecular reactions in the cell, protein homeostasis is critically linked to the survival of all living organisms. Chaperones are key players that maintain protein homeostasis. A sophisticated network of chaperones exists in every organism, and these chaperones fulfill various roles including preventing protein aggregation, disaggregating aggregated proteins and aiding in folding. During the host invasion, bacteria encounter various protein denaturing stresses, such as stomach acid, bile and temperature changes. In this talk, I am particularly focusing on how bacteria respond to bile and temperature changes.